Pablo Burriel Llombart

A Dimer-Seeded Pathway Governs the Nucleation of ProTα-H1 Biomolecular Condensates

This study reveals a dimer-seeded nucleation mechanism for ProTα-H1 biomolecular condensates using simulations and shows how electrostatic screening and protein supersaturation control nucleation and condensate properties.

Size Control of hnRNPK-based Nucleolar Condensates by RNA-Regulated Fusion Dynamics

This study identifies how RNA-regulated fusion dynamics of hnRNPK-based nucleolar condensates prevent coalescence and maintain size control.

Compositional control of FUS condensate ageing through aggregation-prone interaction networks

This study shows how RNA and protein interactions influence the aging of FUS condensates through molecular mechanisms involving LARKS and cross-β-sheet structures.

RNA2PS: A sequence-specific coarse-grained RNA model linking structure, thermodynamics and phase separation

RNA2PS predicts RNA structure and phase separation behavior from sequence, showing sequence-dependent duplex stability and condensation differences in trinucleotide repeat RNAs.

Computational mapping of antibody-receptor energy landscapes to predict membrane internalization

This study uses molecular dynamics simulations to predict antibody internalization by mapping energy landscapes between antibodies and JAM-A receptors, identifying key interactions that drive endocytosis.