Tatsuyuki Yoshii

This paper introduces a method to create synthetic chemo-optogenetic tools by combining rational small-molecule design with TRAP display to generate light-controlled protein binders.

This paper develops synthetic protein condensates that can recruit or release protein activity in mammalian cells using small molecules or light.

This paper introduces a chemogenetic platform that enables rapid, reversible, and repeatable control of plasma membrane protein translocation using a novel engineered tag and ligand pair.