Systemic administration of the mGluR2/3 antagonist LY341495 disrupts reward-related behaviors across ingestive and social domains in mice
Hiroto Inoue, Mizuki Yamamoto, Yuta Tamai, Shuntaro Matsushima, Kota Yamada, Kazuko Hayashi, Koji Toda
This study shows that LY341495, an mGluR2/3 antagonist, reduces reward-related behaviors in mice across ingestive and social domains without affecting general motor function.
Translational Psychiatry · Sep 16, 2026Peer-reviewedNeuroscience