ImmunologybioRxivPreprint
Cytokines mediate increased endothelial-leukocyte interaction and brain capillary plugging during CAR T cell neurotoxicity
Lina Park, Yu-Tung Tsai, Ruoqian Hu…·Juliane Gust
CAR T cell therapy causes cytokine release, leading to increased endothelial-leukocyte interactions and brain capillary plugging, which correlates with neurotoxicity.