Author

Xu Junfa

Guangdong Medical CollegeORCID 0000-0002-3475-5415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1

Frequent Co-Authors

Bangning Cheng· 1 shared Bi‐Feng LiuiD· 1 shared Chen-Ye Lian· 1 shared Chungen Qian· 1 shared Daoshun Wei· 1 shared Fuzhen Xia· 1 shared Gan-Bing Liu· 1 shared Guo-Si Chen· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Bangning Cheng

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2 papers

Recent·Most cited

The circ_0074371/miR-4738-3p/AMPK Signaling Axis Induces M1 Macrophage Polarization and Restricts Intracellular Survival of Mycobacterium tuberculosis

Junai Zhang, Chen-Ye Lian, Yuan-Bin Lu, Shu-Ying Yao, Huan Xu, Yao Xu, Gan-Bing Liu, Guo-Si Chen, Yue-Feng Cen, Yuanting Li, XU Zhuo-lin, Yi-Dan Huang, Guo-Ying Chen, Jia-Jun Wang, Jia-Hua Shi, , Xu Junfa

This study identifies circ_0074371 as a tuberculosis-associated circRNA that regulates AMPK activity and influences macrophage polarization via the miR-4738-3p/AMPK signaling axis, reducing Mtb intracellular survival.

bioRxiv · Oct 26, 2026 · PreprintImmunology

Reconstruction of TrkB complex assemblies and localizing antidepressant targets using Artificial Intelligence

Xufu Xiang, Chungen Qian, Hanbo Yao, Pengjie Li, Bangning Cheng, Daoshun Wei, Wenjun An, Yuming Lu, Ming Chu, Lanlan Wei, Bi‐Feng Liu, Xu Junfa, Xin Liu, Fuzhen Xia

The paper uses AI to reconstruct TrkB complex assemblies and identify antidepressant targets by modeling receptor structures and interactions.

bioRxiv · Feb 21, 2023 · PreprintBioinformatics