Author

Yuming Lu

Shanghai Jiao Tong UniversityPrimary ORCID profile (0000-0002-0183-5574 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Yuming LuiD1 paper · Shanghai Jiao Tong University

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Bangning Cheng· 1 shared Bi‐Feng LiuiD· 1 shared Changrui FengiD· 1 shared Chong-Ping Lai· 1 shared Chungen Qian· 1 shared Da Xie· 1 shared Daoshun Wei· 1 shared Dawei WangiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Bangning Cheng

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2 papers

Recent·Most cited

Sequential Amino Acid Mutagenesis-Driven De Novo Evolution of Adenine Deaminases Enables Efficient In Vivo Base Editing in Primate

Jiaoyang Liao, Hongling Zhang, Shuanghong Chen, Shenlin Hsiao, Chong-Ping Lai, Feng Hu, Wendan Ren, Changrui Feng, Da Xie, Yanqiu Zheng, Wenhui Cai, Wenlong Wang, Yanhong Jiang, Dawei Wang, Erwei Zuo, , Yuming Lu

This paper develops hpABE5.20, a base editor with improved precision and reduced off-target effects through sequential amino acid mutagenesis and AI-based structural prediction.

bioRxiv · May 14, 2025 · PreprintBioengineering

Reconstruction of TrkB complex assemblies and localizing antidepressant targets using Artificial Intelligence

Xufu Xiang, Chungen Qian, Hanbo Yao, Pengjie Li, Bangning Cheng, Daoshun Wei, Wenjun An, Yuming Lu, Ming Chu, Lanlan Wei, Bi‐Feng Liu, Xu Junfa, Xin Liu, Fuzhen Xia

The paper uses AI to reconstruct TrkB complex assemblies and identify antidepressant targets by modeling receptor structures and interactions.

bioRxiv · Feb 21, 2023 · PreprintBioinformatics