Mark J. Connolly

Seizure onset and offset pattern determine the entrainment of the cortex and substantia nigra in the nonhuman primate model of focal temporal lobe seizures

This study examines how seizure onset and offset patterns affect cortical and substantia nigra activity in nonhuman primates, showing pattern-dependent changes in neural coherence and activity.

SAFE-OPT: A Bayesian optimization algorithm for learning optimal deep brain stimulation parameters with safety constraints

SAFE-OPT is a Bayesian optimization algorithm that incorporates safety constraints to find optimal deep brain stimulation parameters without harmful side-effects, validated in rodent studies.

Irregular optogenetic stimulation waveforms can induce naturalistic patterns of hippocampal spectral activity

This study evaluates optogenetic stimulation waveforms on hippocampal spectral activity, finding that irregular patterns better mimic natural activity than standard pulses.