Author

Damian Mikolaj Janecki

Institute of Human GeneticsORCID 0000-0002-3491-1676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Erkut IlaslaniD· 3 shared Jadwiga JaruzelskaiD· 3 shared Kamila Kusz-ZamelczykiD· 3 shared Maciej Jerzy SmialekiD· 3 shared Marcin Piotr SajekiD· 3 shared Maciej KoteckiiD· 2 shared Aleksandra ŚwiercziD· 1 shared Anna SpikiD· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersDevelopmental Biology

Erkut IlaslanORCID

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3 papers

Recent·Most cited

Developmental BiologyInternational Journal of Molecular SciencesPeer-reviewedApr 24, 2020

A male infertility mutation reverts NANOS1 activity from anti-apoptotic to pro-apoptotic by disrupting repression of GADD45A, GADD45B, GADD45G and RHOB genes

Damian Mikolaj Janecki, Erkut Ilaslan, Maciej Jerzy Smialek…·Kamila Kusz-Zamelczyk

The paper identifies a NANOS1 mutation that switches its function from anti-apoptotic to pro-apoptotic in human germ cells by disrupting repression of pro-apoptotic genes.

12 citations

humanbulk RNA-seq

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Molecular BiologyCellsPeer-reviewedApr 16, 2020

Human PUM1 and PUM2 exhibit regulation of divergent mRNA targets in male germ cells

Maciej Jerzy Smialek, Erkut Ilaslan, Marcin Piotr Sajek…·Jadwiga Jaruzelska

The paper identifies distinct mRNA targets and protein cofactors regulated by PUM1 and PUM2 in human male germ cells, revealing functional divergence in their RNA regulatory roles.

19 citations

humanbulk RNA-seq

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Developmental BiologyJournal of Cell SciencePeer-reviewedFeb 24, 2020

Kinesin KIF18A is a novel PUM regulated target promoting mitotic progression and survival of human male germ cell line - TCam-2

Maciej Jerzy Smialek, Bogna Kuczyńska, Erkut Ilaslan…·Jadwiga Jaruzelska

This study identifies KIF18A as a PUM-regulated gene that promotes proliferation and survival in human male germ cell line TCam-2 cells.

5 citations

humanstatistical model

𝕏 PostBluesky