A male infertility mutation reverts NANOS1 activity from anti-apoptotic to pro-apoptotic by disrupting repression of GADD45A, GADD45B, GADD45G and RHOB genes
Damian Mikolaj Janecki, Erkut Ilaslan, Maciej Jerzy Smialek, Marcin Piotr Sajek, Maciej Kotecki, Barbara Ginter-Matuszewska, Anna Spik, Patryk Kraiński, Jadwiga Jaruzelska, Kamila Kusz-Zamelczyk
The paper identifies a NANOS1 mutation that switches its function from anti-apoptotic to pro-apoptotic in human germ cells by disrupting repression of pro-apoptotic genes.
International Journal of Molecular Sciences · Apr 24, 2020Peer-reviewedDevelopmental Biology