Jingyun Yang

This study shows that loss of RHBDL4 in Alzheimer's disease mice increases APP and rescues cognition by reducing proteasomal degradation of β-catenin.

This study performs a meta-analysis of GWAS to identify new genetic loci associated with all-cause and vascular dementia, revealing shared and distinct risk factors.

The paper uses Mendelian randomization and FUMA to identify genetic variants and genes potentially involved in uterine leiomyoma pathogenesis using GWAS summary data.

This study uses Mendelian randomization to identify genes pleiotropically associated with major depressive disorder across multiple brain regions.

This study identifies 15 genetic loci associated with muscle weakness in older adults through a large meta-analysis, revealing new pathways linked to aging and health outcomes.

This study identifies 100 loci associated with mitochondrial DNA copy number and finds causal links between mitochondrial function and mortality.

This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.

The paper identifies 25 genetic loci associated with subcortical brain structure volumes in over 40,000 individuals, revealing novel biology and potential drug targets.