Author

Darren J. Hart

Centre National de la Recherche ScientifiqueORCID 0000-0002-3502-2002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Alberto Florez PradaiD· 3 shared Camile Bourgneuf· 1 shared Catherine IseliD· 1 shared Chantal PichoniD· 1 shared Chloé SturmachiD· 1 shared Didier BoturyniD· 1 shared Guido UguzzoniiD· 1 shared Nabila LarouiiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBioinformatics

Alberto Florez PradaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

mock-fastq-generator: A synthetic FASTQ generator

Alberto Florez Prada, Darren J. Hart

mock-fastq-generator creates synthetic FASTQ files for testing bioinformatics pipelines without using biological data.

SoftwareX · Oct 30, 2026Peer-reviewedBioinformatics

Affinity-enhanced peptides delivered by mRNA-LNPs inhibit influenza A virus replication by disrupting the PA-PB1 interaction

Alberto Florez Prada, Chloé Sturmach, Nabila Laroui, Nicolas Pautrieux, Camile Bourgneuf, Philippe J. Mas, Rémy Lartia, Didier Boturyn, Wim Pascal Burmeister, Chantal Pichon, Nadia Naffakh, Catherine Isel, Darren J. Hart

The paper identifies and delivers peptides that disrupt the PA-PB1 interaction in influenza polymerase, inhibiting viral replication in cultured cells.

bioRxiv · Jul 31, 2026 · PreprintMicrobiology

Calculation of sequence space coverage in a mutagenesis library

Alberto Florez Prada, Guido Uguzzoni, Darren J. Hart

This paper introduces a scalable algorithm to calculate exact discovery probabilities in mutagenesis libraries and provides an open-source tool for experimental design.

bioRxiv · Jun 18, 2026 · PreprintBioinformatics