Probing the activity of cysteine cathepsins in inflammatory bowel diseases
Bethany M. Anderson, Alexander R. Ziegler, Rhiannon I. Campden…·Laura E. Edgington‐Mitchell
This study investigates the role of cathepsin S and X in inflammatory bowel diseases using activity-based probes and mouse models, finding that cathepsin S contributes to some symptoms but pharmacologic inhibition may have unintended effects.