Cell BiologybioRxivPreprint
Clathrin differentially adapts its trimerisation domain during mammalian evolution to traffic the insulin-responsive GLUT4 glucose transporter
George T. Bates, Will P. Bultitude, Joshua Greig…·Frances M. Brodsky
The paper identifies an alternatively-spliced form of CHC17 (CHC17-SAS) that compensates for the absence of CHC22 in some vertebrates, enabling GLUT4 trafficking.
DOI 10.64898/2026.08.20.745084