Tien M. Pham

A Practical Framework for Constructing Population-Specific and Alternate-Contig-Aware Genome References: A case study of Vietnam

This paper introduces a framework for creating population-specific genome references using alternate-contig awareness, demonstrating improved variant calling in Vietnamese populations compared to GRCh38.

VN1K: a genome graph-based and function-driven multi-omics and phenomics resource for the Vietnamese population

VN1K provides a comprehensive multi-omics and phenomics resource for the Vietnamese population, identifying novel variants and functional associations with disease traits and drug responses.

Integrating polygenic and transcriptional risk scores improves risk prediction of nine common diseases in the underrepresented Vietnamese population