GenomicsbioRxivPreprint
A Practical Framework for Constructing Population-Specific and Alternate-Contig-Aware Genome References: A case study of Vietnam
Trang T. H. Tran, Vinh C. Duong, Nam N. Nguyen…·Nam S. Vo
This paper introduces a framework for creating population-specific genome references using alternate-contig awareness, demonstrating improved variant calling in Vietnamese populations compared to GRCh38.
DOI 10.64898/2026.08.24.746817