Author

Hoang Nguyen

Brigham and Women's HospitalPrimary ORCID profile (0000-0001-6910-7269 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Hoang NguyeniD3 papers · Texas Biomedical Research Institute

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:E. coli· 1

Frequent Co-Authors

Benjamin K. Eschle· 1 shared Brittaney A. LeeperiD· 1 shared Changxu PangiD· 1 shared Chi Trung HaiD· 1 shared Christopher Alexander FrenchiD· 1 shared Cuong Le· 1 shared Dat T. Nguyen· 1 shared Dat X. Dao· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

Benjamin K. Eschle

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BET BD2 inhibition facilitates SPOP-mediated degradation of chromatin-associated BRD4/BRD4-NUT, a therapeutic vulnerability in NUT carcinoma

Kathleen Bates, Hoang Nguyen, Kyle P. Eagen, Julianna Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Benjamin K. Eschle, Stacey T Gray, Krupa Sampat, Taylor R Durall, Jia Luo, Geoffrey Ira Shapiro, Steven J. Ferrara, Jacob Gillis, Dustin Rogers, , Christopher Alexander French

The paper shows that selective inhibition of BRD4-BD2 promotes SPOP-mediated degradation of BRD4/BRD4-NUT in NUT carcinoma, leading to better therapeutic outcomes than pan-BET inhibition.

bioRxiv · Aug 19, 2026 · PreprintCancer Biology

VN1K: a genome graph-based and function-driven multi-omics and phenomics resource for the Vietnamese population

Trang T. H. Tran, Tham H. Hoang, Mai Hoang Tran, Tien M. Pham, Nam N. Nguyen, Giang M. Vu, Vinh C. Duong, Quang T. Vu, Nguyen T. Nguyen, Vu Quoc Hien, Nguyen Minh Trang, Thien K. Nguyen, Sang V. Nguyen, Toan Dang, Hoang Nguyen, , Nam S. Vo

VN1K provides a comprehensive multi-omics and phenomics resource for the Vietnamese population, identifying novel variants and functional associations with disease traits and drug responses.

Nature Communications · Jul 22, 2026Peer-reviewedGenomics

Cryo-electron microscopy structures of a zinc uptake ABC transporter

Changxu Pang, Hoang Nguyen, Qingfang Zhang, İvet Bahar, Qun Liu

The paper reports cryo-EM structures of the Zn2+ ABC transporter ZnuB-ZnuC from E. coli, revealing a self-regulating mechanism via a zinc sensor.

Structure · May 20, 2026Peer-reviewedBiochemistry