Author

Abigail E. Burgess

University of OtagoORCID 0000-0002-3522-6347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Hunter G. NyvalliD· 1 shared Jack R. CurryiD· 1 shared Jessica L. DunlopiD· 1 shared John E. BurkeiD· 1 shared Liam S. TurkiD· 1 shared Pavel FilipčíkiD· 1 shared Peter D. MaceiD· 1 shared Sam A. JamiesoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Hunter G. NyvallORCID

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1 paper

Recent·Most cited

DET1 dynamics underlie co-operative ubiquitination by CRL4DET1 COP1 complexes

Abigail E. Burgess, Tarren A. Loughran, Liam S. Turk, Hunter G. Nyvall, Jessica L. Dunlop, Sam A. Jamieson, Jack R. Curry, John E. Burke, Pavel Filipčík, Simon H. J. Brown, Peter D. Mace

The paper reports the cryo-EM structure of human DET1 in complex with DDB1-DDA1 and Ube2e2, revealing how DET1 dynamics facilitate COP1 recruitment and ubiquitination.

Science Advances · Feb 26, 2025Peer-reviewedBiochemistry