Lukas Westermann

The paper develops a transcriptome-based method to match bulk RNA-seq data from kidney cell lines to single-cell reference datasets, identifying accurate cell type identities and evaluating method performance.

This paper develops a deep learning pipeline to quantify epithelial cell shape and tight junctions, applied to ADPKD models and Drosophila egg chambers to study morphogenetic changes.

This study investigates DNAJB11's role in atypical ADPKD, showing biallelic loss causes cystic kidney disease and identifying impaired PC1 cleavage as a potential mechanism.