Clonal relationships between Tph and Tfh cells in patients with SLE and in murine lupus
Takanori Sasaki, John M. Sowerby, Yinan Xiao, Runci Wang, Snigdha Samarpita, Tatsuki Abe, Kathryne E. Marks, Alice Horisberger, Yidan Gao, Pui Y. Lee, Yujie Qu, Marc A. Sze, Stephen E. Alves, Marc C. Levesque, Keishi Fujio, , Deepak A. Rao
This study shows clonal overlap between Tph and Tfh cells in SLE patients and mice, suggesting shared developmental pathways and potential implications for immunosuppressive treatment.
bioRxiv · Jan 27, 2025 · PreprintImmunology