Author

Karen H. Costenbader

Brigham and Women's HospitalORCID 0000-0002-8972-9388Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alice HorisbergeriD· 1 shared Chikashi C. TeraoiD· 1 shared Deepak A. RaoiD· 1 shared Elizabeth W. KarlsoniD· 1 shared Jing CuiiD· 1 shared John M. SowerbyiD· 1 shared Kamil SlowikowskiiD· 1 shared Katherine P. LiaoiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Alice HorisbergerORCID

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2 papers

Recent·Most cited

Clonal relationships between Tph and Tfh cells in patients with SLE and in murine lupus

Takanori Sasaki, John M. Sowerby, Yinan Xiao, Runci Wang, Snigdha Samarpita, Tatsuki Abe, Kathryne E. Marks, Alice Horisberger, Yidan Gao, Pui Y. Lee, Yujie Qu, Marc A. Sze, Stephen E. Alves, Marc C. Levesque, Keishi Fujio, , Deepak A. Rao

This study shows clonal overlap between Tph and Tfh cells in SLE patients and mice, suggesting shared developmental pathways and potential implications for immunosuppressive treatment.

bioRxiv · Jan 27, 2025 · PreprintImmunology

Using genetics to differentiate patients with similar symptoms: application to inflammatory arthritis in the rheumatology outpatient clinic

Rachel Knevel, Saskia le Cessie, Chikashi C. Terao, Kamil Slowikowski, Jing Cui, Tom W. J. Huizinga, Karen H. Costenbader, Katherine P. Liao, Elizabeth W. Karlson, Soumya Raychaudhuri

This paper develops G-Prob, a method converting genetic data into disease probabilities for inflammatory arthritis, improving diagnostic accuracy in rheumatology.

bioRxiv · Oct 22, 2019 · PreprintGenetics