Diversity of motility gene signatures distinguishes commensal Clostridiathat elicit divergent host immune responses
Lennard Wayne Duck, Melissa S. Jennings, Jung-Shan Hsu, Covenant Femi Adeboboye, E. Leighann Morgan, Kiarra J. Coger, Barbara J. Klocke, Dave D. Hill, Katie L. Alexander, Alexander F. Rosenberg, Goo Lee, Qing Sheng Zhao, Charles O. Elson, Craig L. Maynard
The paper identifies distinct motility gene signatures in Clostridia that correlate with divergent immune responses, showing one group promotes inflammation while another induces tolerance.
bioRxiv · Jul 18, 2025 · PreprintImmunology