Author

Lennard Wayne Duck

University of Alabama at BirminghamORCID 0000-0002-4746-4959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Alexander F. Rosenberg· 1 shared Barbara J. KlockeiD· 1 shared Blake F. FreyiD· 1 shared Carlene L. ZindliD· 1 shared Casey Todd WeaveriD· 1 shared Charles O. ElsoniD· 1 shared Christopher Garrett Wilson· 1 shared Chuan Xing· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Alexander F. Rosenberg

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2 papers

Recent·Most cited

Barrier Immune Memory is Promoted by Intestinal Epithelial Cell Presentation of Injected Bacterial Antigens

Christopher Garrett Wilson, Pragun Acharya, Laura Karsch, Lennard Wayne Duck, Nana Twumasi-Ankrah, Yuanyou Wang, Hongxing Shen, Chuan Xing, Blake F. Frey, Vishal H. Oza, Stacey N. Harbour, Yoshiko Nagaoka-Kamata, Jeffrey R. Singer, Robin D. Hatton, Jeffrey R. Moffitt, , Casey Todd Weaver

The paper shows that CD4 T cell memory is enhanced when antigens are presented by intestinal epithelial cells rather than bacterial proteins.

bioRxiv · Mar 31, 2026 · PreprintImmunology

Diversity of motility gene signatures distinguishes commensal Clostridiathat elicit divergent host immune responses

Lennard Wayne Duck, Melissa S. Jennings, Jung-Shan Hsu, Covenant Femi Adeboboye, E. Leighann Morgan, Kiarra J. Coger, Barbara J. Klocke, Dave D. Hill, Katie L. Alexander, Alexander F. Rosenberg, Goo Lee, Qing Sheng Zhao, Charles O. Elson, Craig L. Maynard

The paper identifies distinct motility gene signatures in Clostridia that correlate with divergent immune responses, showing one group promotes inflammation while another induces tolerance.

bioRxiv · Jul 18, 2025 · PreprintImmunology