Author
Garvan Institute of Medical ResearchORCID 0000-0002-3560-4125Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jeremy Z. R. Han, Monica Phimmachanh, Jordan F. Hastings…·David R. Croucher
The paper identifies JNK-independent drugs that, when combined with standard chemotherapy, improve response in relapsed high-risk neuroblastoma by exploiting differential apoptotic network utilization.
Sharissa L. Latham, Yolande E. I. O’Donnell, Oscar Girgis-Cook…·David R. Croucher
The paper identifies a selective JNK inhibitor that blocks metastasis in triple-negative breast cancer by targeting metabolic pathways.
Christopher R. Horne, Toby A. Dite, Samuel N. Young…·James M. Murphy
The paper identifies allosteric regulation of PSKH1 kinase activity by Ca2+ sensor proteins, showing both activation and suppression by different sensors.
Sarah Alexandrou, Christine S Lee, Kristine J. Fernandez…·Catherine Elizabeth Caldon
This study identifies JNK pathway suppression as a driver of resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer, with implications for patient stratification.