Mehrzad Samadi

DeepSAP improves RNA-seq alignment by combining transcriptome-guided alignment with a transformer-based model for splice junction scoring, achieving the highest F1 score on simulated datasets.

Parabricks accelerates genomic analysis using GPU acceleration, reducing processing time while maintaining accuracy across various sequencing modalities.

The paper identifies de novo variants in the 1000 Genomes Project using a GPU-based workflow, revealing cell line artifacts and cancer-related mutation profiles.