The single pass membrane protein MRAP2 regulates energy homeostasis by promoting primary cilia localization of the G protein-coupled receptor MC4R
Adélaïde Bernard, Irene Ojeda Naharros, Florence Bourgain‐Guglielmetti, Jordi Ciprin, Xinyu Yue, Sumei Zhang, Erin McDaid, Maxence V. Nachury, Jeremy F. Reiter, Christian Vaisse
This study shows that MRAP2 is essential for MC4R's localization to primary cilia and its role in regulating energy homeostasis and body weight.
bioRxiv · Nov 13, 2020 · PreprintNeuroscience