A pancreas specific Ptf1a-driven Cre mouse line causes paternally transmitted germline recombination
Derya Kabacaoğlu, Dietrich Alexander Ruess, Kıvanç Görgülü, Katja Steiger, Marina Lesina, Hana Algül
The paper reports germline recombination in Ptf1a-driven Cre mouse lines when the Cre allele is paternally transmitted, emphasizing the need for genotyping and maternal transmission to avoid unintended recombination.
Gastroenterology · Jun 24, 2021Peer-reviewedGenetics