Author

Marina Lesina

Technical University of MunichORCID 0000-0001-8427-3548Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Dietrich Alexander RuessiD· 2 shared Hana AlgüliD· 2 shared Katja SteigeriD· 2 shared Kıvanç GörgülüiD· 2 shared Alexandra BerningeriD· 1 shared Bruno SáinziD· 1 shared C. Dai· 1 shared D. Bakırdöğen· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Dietrich Alexander RuessORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyMolecular CancerPeer-reviewedDec 15, 2025

c-Rel drives pancreatic cancer metastasis through Fibronectin-Integrin signaling-induced isolation stress resistance and EMT activation

D. Bakırdöğen, Kıvanç Görgülü, J. Xin…·Hana Algül

This study identifies c-Rel as a driver of pancreatic cancer metastasis by promoting EMT, ECM remodeling, and resistance to isolation stress through fibronectin-integrin signaling.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsGastroenterologyPeer-reviewedJun 24, 2021

A pancreas specific Ptf1a-driven Cre mouse line causes paternally transmitted germline recombination

Derya Kabacaoğlu, Dietrich Alexander Ruess, Kıvanç Görgülü…·Hana Algül

The paper reports germline recombination in Ptf1a-driven Cre mouse lines when the Cre allele is paternally transmitted, emphasizing the need for genotyping and maternal transmission to avoid unintended recombination.

2 citations

mouseexperimental assay

𝕏 PostBluesky