NeurosciencebioRxivPreprint
Silencing neuroinflammatory reactive astrocyte activating factors ameliorates disease outcomes in perinatal white matter injury
Patricia Renz, Daniel Surbek, Valérie Haesler…·Amanda Brosius Lutz
This study shows that reducing C3-expressing reactive astrocytes in a mouse model of perinatal white matter injury improves myelination and behavioral outcomes, and identifies these cells as potential therapeutic targets in human WMI.
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