Author

Amanda Brosius Lutz

University Hospital of BernORCID 0000-0002-6063-0480Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Aditi AgrawaliD· 1 shared Aditi Vichare· 1 shared Alejandro A. GranadosiD· 1 shared Alexandra E. MünchiD· 1 shared Andreina SchoeberleiniD· 1 shared Arun P. Thottumkara· 1 shared Ashley K. Yeh· 1 shared Daniel SurbekiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Aditi AgrawalORCID

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2 papers

Recent·Most cited

Silencing neuroinflammatory reactive astrocyte activating factors ameliorates disease outcomes in perinatal white matter injury

Patricia Renz, Daniel Surbek, Valérie Haesler, Vera Tscherrig, Eric Jinsheng Huang, Manideep Chavali, Shane Antony Liddelow, David H. Rowitch, Andreina Schoeberlein, Amanda Brosius Lutz

This study shows that reducing C3-expressing reactive astrocytes in a mouse model of perinatal white matter injury improves myelination and behavioral outcomes, and identifies these cells as potential therapeutic targets in human WMI.

bioRxiv · Dec 19, 2022 · PreprintNeuroscience

Schwann cells promote sensory neuron excitability during development

Husniye Kantarci, Pablo D. Elvira, Arun P. Thottumkara, Manasi Iyer, Lauren J. Donovan, Micaela Q. Dugan, Nicholas Ambiel, Emma M. O’Connell, Alejandro A. Granados, Hong Zeng, Nay Lui Saw, Amanda Brosius Lutz, Steven A. Sloan, Erin E. Gray, Khanh V. Tran, , J. Bradley Zuchero

This study shows Schwann cells promote sensory neuron excitability during development by secreting prostaglandin E2, which is essential for normal sodium channel expression and action potential firing.

bioRxiv · Oct 31, 2022 · PreprintNeuroscience