The 3D genomics of lampbrush chromosomes highlights the role of active transcription in chromatin organization
Timofey A. Lagunov, Maria M. Gridina, Artem R. Nurislamov…·Veniamin Fishman
This paper integrates single-cell Hi-C, RNA-seq, and microscopy to uncover how hypertranscription shapes lampbrush chromosome structure through transcription-dependent chromatin organization.