A translocation-competent pore is required for Shigella flexneri to escape from the double membrane vacuole during intercellular spread
Julie E. Raab, Tucker B. Harju, Jody D. Toperzer, Jeffrey K. Duncan-Lowey, Connon I. Thomas, Anza Darehshouri, Marcia B. Goldberg, Brian C. Russo
This study shows that IpaC forms a translocation-competent pore essential for Shigella flexneri to escape double membrane vacuoles during intercellular spread.
mBio · Aug 11, 2025Peer-reviewedMicrobiology