Janet F. Kelso

SyMetrics evaluates the pathogenicity of synonymous variants using a machine learning model that integrates multiple predictors, achieving high accuracy in distinguishing deleterious from benign variants.

quicksand is a Nextflow pipeline for rapid and accurate taxonomic classification of sedaDNA mtDNA, achieving comparable accuracy to existing methods with reduced runtime.

This paper presents a second high-quality Denisovan genome from a 200,000-year-old molar, revealing genetic contributions from multiple Denisovan groups and refining the Denisovan genetic lineage.

The paper shows that reference bias causes branch length variation in Y chromosome phylogeny and proposes masking fast-evolving regions to improve accuracy.

The paper reports a high-coverage Neandertal genome from Chagyrskaya Cave, revealing genetic features unique to Neandertals and population structure insights.

The paper compares gene diversity in Neandertals, Denisovans, and present-day humans, finding lower diversity in archaic humans, especially in immune-related genes, but no significant decrease over time in Neandertals.

The paper analyzes ancient genomes from Finland and Northwest Russia to show Siberian ancestry in northern Europe dates back 3,500 years and influenced modern Uralic-speaking populations.