Felix M. Key

AccuSNV is a deep learning tool for high-accuracy bacterial SNV calling that outperforms existing methods in simulated and real datasets.

The paper reconstructs 3,500 years of sheeppox virus evolution using ancient genomes from archaeological and medieval parchment sources, showing divergence events and gene inactivation.

The paper tracks the colonization and evolution of opportunistic pathogens in critically ill patients, identifying a mutation linked to healthcare-associated infections.

The paper presents a Yersinia pestis genome from a Bronze Age sheep, showing it belongs to a lineage previously only found in ancient humans and suggests transmission via livestock.

The paper examines ancient pathogens in zooarchaeological remains to identify zoonotic diseases and validate their authenticity using genetic and palaeopathological methods.

HOPS automates the detection and authentication of bacterial DNA in ancient DNA samples to identify candidates for genomic analysis.

The paper compares gene diversity in Neandertals, Denisovans, and present-day humans, finding lower diversity in archaic humans, especially in immune-related genes, but no significant decrease over time in Neandertals.

The paper identifies a genetic variant associated with cold adaptation in humans, showing a latitudinal cline and linking it to migraine prevalence.