Aida M. Andrés

This study uses non-invasive fecal samples and chromosome 21 target capture sequencing to analyze bonobo population structure, identifying three subpopulations and river barriers influencing genetic differentiation.

The paper identifies 18 mitochondrial variants associated with climate adaptation using a large dataset of human mtDNA and climate variables.

The paper quantifies how many genomic loci under balancing selection are detectable versus invisible to standard tests, showing detectable loci are a biased subset with large fitness effects.

This study presents the first whole-genome sequencing of Sudanese populations, revealing complex admixture history and adaptive genetic variants related to malaria resistance in Sudanese Copts.

The paper identifies human-specific gene expansions linked to brain evolution by analyzing genome sequences and functional models in zebrafish.

This study identifies local genetic adaptation to habitat in wild chimpanzees, particularly to pathogens like malaria, using newly generated exomes.

This paper identifies three genetically distinct bonobo populations with inferred geographic origins and estimates split times and effective population sizes, highlighting the need for conservation attention to substructure.

The paper reconstructs and assays ancient enzymes to show that losing selenocysteine in GPX6 led to functional loss and convergent evolution in mammalian oxidoreductases.

The paper studies 45 common human polymorphic inversions, showing their functional and evolutionary impact, including gene disruption and association with phenotypic traits.

The paper analyzes genetic variation in chimpanzees and bonobos to show how demographic history affects purifying selection and identifies lineage-specific functional changes linked to reproductive differences.

The paper compares gene diversity in Neandertals, Denisovans, and present-day humans, finding lower diversity in archaic humans, especially in immune-related genes, but no significant decrease over time in Neandertals.

The paper identifies a genetic variant associated with cold adaptation in humans, showing a latitudinal cline and linking it to migraine prevalence.

The paper introduces NCD2, a statistic to detect long-term balancing selection in human genomes, finding it affects 0.6% of genomic windows and 0.8% of positions, with many novel targets.

The paper identifies adaptive introgression of TLR6-TLR1-TLR10 haplotypes from Neandertals and Denisovans in modern humans, linked to immune traits and disease phenotypes.