Zhaoli Liu

This study shows PD-1 is essential for early HBV-specific CD8+ T cell expansion and survival during acute infection but does not suppress effector cytokine function, and its absence impairs proliferation and promotes exhaustion in chronic infection.

This study investigates how DNA methylation changes after BCG vaccination influence cytokine responses and identifies epigenetic pathways mediating genetic effects on immune responses.

CellDemux demultiplexes genetically labeled single-cell and single-nuclei libraries across modalities, achieving 88% donor assignment accuracy in benchmarking.