Author

Wenchao Li

Medizinische Hochschule HannoverORCID 0000-0002-7956-0742Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Yang LiiD· 3 shared Ahmed AlaswadiD· 2 shared Cheng‐Jian XuiD· 2 shared Mihai Gheorghe NeteaiD· 2 shared Zhaoli LiuiD· 2 shared Ahmed Essam MahfouziD· 1 shared Aida Ripoll-CladellasiD· 1 shared Andrei S. SarleaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersGenetics

Yang LiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Federated single-cell QTL meta-analysis reveals novel disease mechanisms

Dan Kaptijn, Lieke Michielsen, Drew R. Neavin, Aida Ripoll-Cladellas, José Alquicira-Hernández, Maryna Korshevniuk, Jimmy Tsz Hang Lee, Roy Oelen, Martijn Vochteloo, Robert Warmerdam, Yoshinari Ando, Maria Ban, Odmaa Bayaara, Marijn Berg, Irene V. van Blokland, , Monique G.P. van der Wijst

The paper performs a federated cis-eQTL meta-analysis across single-cell datasets to identify cell-type-specific genetic effects and link them to disease mechanisms.

bioRxiv · Apr 14, 2026 · PreprintGenetics

Epigenetic Reprogramming Mediates Monocyte and Heterologous T Cell-derived Cytokine Responses after BCG Vaccination

Cancan Qi, Zhaoli Liu, Gizem Kılıç, Andrei S. Sarlea, Priya A. Debisarun, Xuan Liu, Yonatan Ayalew Mekonnen, Wenchao Li, Martin Graßhoff, Ahmed Alaswad, Apostolos Petkoglou, Valerie A. C. M. Koeken, Simone J.C.F.M. Moorlag, L. Charlotte J. de Bree, Vera P. Mourits, , Cheng‐Jian Xu

This study investigates how DNA methylation changes after BCG vaccination influence cytokine responses and identifies epigenetic pathways mediating genetic effects on immune responses.

medRxiv · Mar 27, 2024 · PreprintGenetic & Genomic Medicine

CellDemux: coherent genetic demultiplexing in single-cell and single-nuclei experiments.

Martijn Zoodsma, Qiuyao Zhan, Saumya Kumar, Javier Botey-Bataller, Wenchao Li, Liang Zhou, Ahmed Alaswad, Zhaoli Liu, Zhenhua Zhang, Bowen Zhang, Cheng‐Jian Xu, Yang Li

CellDemux demultiplexes genetically labeled single-cell and single-nuclei libraries across modalities, achieving 88% donor assignment accuracy in benchmarking.

bioRxiv · Jan 18, 2024 · PreprintGenomics