Author

Emma Heckenberg

ORCID 0000-0002-3646-4283Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Caitlin Hale· 2 shared Carolyn B. CoyneiD· 2 shared Jacob G. DavisiD· 1 shared Justin T. SteppeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersImmunology

Caitlin Hale

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 25, 2026

Type I and Type III Interferons Differentially Shape Antiviral Defense and Epithelial Integrity at the Choroid Plexus

Justin T. Steppe, Emma Heckenberg, Caitlin Hale, Carolyn B. Coyne

This study investigates the differential roles of type I and III interferons in antiviral defense and epithelial integrity at the choroid plexus using organoid models and single-cell RNA sequencing.

DOI 10.64898/2026.02.10.705109

humanmouse

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MicrobiologybioRxivPreprintAug 12, 2025

Tissue-Resident Macrophage and Dendritic Cell Cooperation Drives Type I IFN Immunity to Enteroviruses in the Liver

Emma Heckenberg, Jacob G. Davis, Caitlin Hale, Carolyn B. Coyne

This study identifies Kupffer cells and dendritic cells as key sources of type I IFN during echovirus infection, showing their role in liver immunity and pathogenesis.

1 citation

mousescRNA-seq

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