Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-viral hsa-miR-132 Processing
Verena Schlösser, Helen Louise Lightfoot, Christine Leemann, Aathma Merin Bejoy, Shashank Tiwari, Jeffrey L. Schloßhauer, Valentina Vongrad, Andreas Brunschweiger, Jonathan Hall, Karin Jutta Metzner, Jochen Imig
This study shows Enoxacin reduces HIV-1 replication by downregulating hsa-miR-132-3p in T-cells, suggesting potential for antiviral therapy through miRNA modulation.
bioRxiv · Nov 10, 2024 · PreprintMolecular Biology