Lauren Mashburn‐Warren

This study uses optical genome mapping to detect somatic structural variants in epilepsy brain tissue, revealing variants missed by short-read sequencing and providing insights into their mechanisms.

The paper identifies somatic RAS-MAPK pathway activating variants in hippocampal sclerosis patients, linking them to seizure-induced injury and suggesting therapeutic targets.

This study shows that Porphyromonas gingivalis outer membrane vesicles reduce cortical neuron density and increase Tau phosphorylation in embryonic mouse brains without affecting dam or pup weights.