Author

Martine Simonelig

Centre National de la Recherche ScientifiqueORCID 0000-0002-3731-6979Unclaimed ORCID profile · follow to get notified of new preprints

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Martine Simonelig1 paper

Biology Disciplines

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Developmental Biology· 4 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:Drosophila· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:multiome· 2 Approach:statistical model· 2 Assay:metagenomics· 1

Frequent Co-Authors

Aymeric Chartier· 4 shared Anne RamatiD· 2 shared Céline Garret· 2 shared Julie Cremaschi· 2 shared Patricia Rojas‐RíosiD· 2 shared Stéphanie Pierson· 2 shared Adel BoughlitaiD· 1 shared Amandine BastideiD· 1 shared

Activity by Year

2014-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersDevelopmental Biology

Aymeric Chartier

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Author profile →

5 papers

Recent·Most cited

piRNAs are regulators of metabolic reprogramming in stem cells

Patricia Rojas‐Ríos, Aymeric Chartier, Camille Enjolras, Julie Cremaschi, Céline Garret, Adel Boughlita, Anne Ramat, Martine Simonelig

This study identifies piRNAs and the PIWI protein Aubergine as regulators of glycolytic metabolism in Drosophila germline stem cells.

Nature Communications · Sep 27, 2024Peer-reviewedDevelopmental Biology

RNF219 regulates CCR4-NOT function in mRNA translation and deadenylation

Aude Guénolé, Fabien Velilla, Aymeric Chartier, April Rich, Anne‐Ruxandra Carvunis, Claude Sardet, Martine Simonelig, Bijan Sobhian

This study identifies RNF219 as an interacting partner of the CCR4-NOT complex that modulates its translational repression activity through deadenylation-independent mechanisms.

Scientific Reports · Jun 3, 2022Peer-reviewedMolecular Biology

The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm

Anne Ramat, María Rosa García-Silva, Camille Jahan, Rima Naït-Saïdi, Jérémy Dufourt, Céline Garret, Aymeric Chartier, Julie Cremaschi, Vipul Patel, Mathilde Decourcelle, Amandine Bastide, François Juge, Martine Simonelig

This study identifies a new role for the PIWI protein Aubergine in promoting nanos mRNA translation by interacting with eIF3 and PABP in Drosophila germ plasm.

Cell Research · Mar 4, 2020Peer-reviewedDevelopmental Biology

Aubergine And piRNAs Repress The Proto-Oncogene Cbl For Germline Stem Cell Self-Renewal

Patricia Rojas‐Ríos, Aymeric Chartier, Stéphanie Pierson, Martine Simonelig

This study shows Aubergine and piRNAs repress Cbl mRNA translation to regulate germline stem cell self-renewal and differentiation in Drosophila.

The EMBO Journal · Oct 13, 2017Peer-reviewedDevelopmental Biology

Orb prevents autophagy in the Drosophila germline through translational repression of Atg12 mRNA

Isabelle Busseau, Stéphanie Pierson, Dany Séverac, Christelle Dantec, Martine Simonelig

This study shows Orb represses autophagy in Drosophila germline by inhibiting Atg12 mRNA translation, preventing cell death during early oogenesis.

bioRxiv · Aug 15, 2014 · PreprintDevelopmental Biology