Mathilde Decourcelle

A generalizable normalization framework to decouple protocol and instrument effects: Application to high-sensitivity proteomics multicentric study (PME13)

This paper introduces a normalization framework to decouple protocol and instrument effects in multicenter proteomics studies, demonstrating its application to the PME13 dataset.

A reciprocal interplay between 5-HT2A and mGlu5 receptors underlies neuroplasticity

This study shows that psychedelics induce neuroplasticity through a reciprocal interaction between 5-HT2A and mGlu5 receptors involving Shank3.

Pervasive translation of the downstream ORF from bicistronic mRNAs by human cells: impact of the upstream ORF codon usage and splicing

This study demonstrates that human cells can translate downstream ORFs in bicistronic mRNAs, showing that upstream ORF codon usage and splicing affect downstream translation efficiency.

Transcriptomic, proteomic and functional consequences of codon usage bias in human cells during heterologous gene expression.

This study examines how codon usage bias affects gene expression and cellular function in human cells during heterologous gene expression, showing significant transcriptomic, proteomic, and functional differences.

The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm

This study identifies a new role for the PIWI protein Aubergine in promoting nanos mRNA translation by interacting with eIF3 and PABP in Drosophila germ plasm.