Microtubule Engagement by the WD40-Containing Tail of Kinesin-4 KIF21B
Aryan Taheri, Benjamin J. LaFrance, Julia Peukes, Ankit Rai, Anna S. Akhmanova, Eva Nogales
This study uses cryo-EM and cryo-ET to reveal how the WD40 domain of KIF21B interacts with microtubules, identifying two binding states and suggesting its role in microtubule regulation.
bioRxiv · Jul 30, 2026 · PreprintBiochemistry