Julia Peukes

This study investigates how tau protein regulates motor proteins on microtubules using single-molecule imaging, cryo-EM, and MD simulations, revealing distinct mechanisms for inhibiting kinesin-1 and dynein.

This study uses cryo-EM and cryo-ET to reveal how the WD40 domain of KIF21B interacts with microtubules, identifying two binding states and suggesting its role in microtubule regulation.

This paper introduces two fluorescence-guided cryo-FIB milling workflows to improve targeting accuracy for cryo-ET, enabling routine capture of structures across spatial scales.

AreTomo3 and DenoisET form an automated GPU pipeline that reconstructs cryo-electron tomograms with tile-based contrast transfer function correction, screens their quality, and denoises them during acquisition.

This study engineers a minimal EDV for genome editing by removing viral components, showing improved efficiency and reduced size.

This paper develops a physical model explaining how M1 protein polymerization into helices facilitates efficient influenza A virus assembly and membrane deformation.

This study uses cryo-electron tomography to reveal the 3D molecular architecture of glutamatergic synapses in the adult mammalian forebrain, showing a synaptoplasm rather than a distinct PSD.