Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
Noah J. Smith, Rashika Joshi, Hitesh Desmukh…·Brian Michael Varisco
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Cincinnati Children's Hospital Medical CenterORCID 0000-0002-3735-1360Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Noah J. Smith, Rashika Joshi, Hitesh Desmukh…·Brian Michael Varisco
Joseph Stevens, Erica Culberson, Jeremy Michael Kinder…·Hitesh S. Deshmukh
This study identifies microbiota-derived inosine as a key factor in promoting CD8+ T cell responses against influenza in newborns by reversing epigenetic dysregulation.
Andrea Tóth, Shelby H. Steinmeyer, Paranthaman Senthamarai Kannan…·William J. Zacharias
This study shows that blocking inflammation in preterm primates prevents lung injury, preserving alveolar structure and function similar to chronic lung disease in newborns.