Andrea Tóth

This study models early IAV infection in alveolar organoids, revealing conserved AT2 cell responses and uninfected cell state transitions driven by inflammation.

The paper shows that alveolar-basal intermediates (ABI) drive pulmonary fibrosis by coordinating a pro-fibrotic signaling niche in silicosis.

This study shows that PRC2 maintains AT2 cell fate in the adult lung by preventing transitions to ABI and basal-like states, both in vitro and in vivo.

The paper investigates the role of Cux1 in postnatal epithelial development, finding that its loss causes transient developmental delays in multiple tissues without affecting organogenesis or regeneration.

This study identifies Nkx2-1-driven chromatin topology changes in alveolar epithelial progenitor cells that regulate lung regeneration and differentiation.

This study shows that blocking inflammation in preterm primates prevents lung injury, preserving alveolar structure and function similar to chronic lung disease in newborns.