Author

Simona Granata

University of CalabriaORCID 0000-0002-3740-7598Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Francesca LuganiiD· 2 shared Gianluigi ZazaiD· 2 shared Adele MitrottiiD· 1 shared Aftab S. ChishtiiD· 1 shared Akchurin Oleh· 1 shared Alberto MagnascoiD· 1 shared Alejandro Quiroga· 1 shared Andrea Garbarino· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPathology

Francesca LuganiORCID

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2 papers

Recent·Most cited

IgM hyposialylation drives podocyte injury in pediatric and young adult patients with podocytopathies.

Sonia Spinelli, Andrea Garbarino, Francesca Lugani, Edoardo La Porta, Andrea Petretto, Martina Bartolucci, Chiara Lavarello, Nicole Grinovero, Sofia Gaudiano, Ilaria Musante, Paolo Scudieri, Antonella Trivelli, Giorgio Piaggio, Alberto Magnasco, Maria Ludovica Degl’Innocenti, , Maurizio Bruschi

This study shows that reduced sialylation of IgM in patients with podocytopathies correlates with disease activity and causes podocyte injury through oxidative stress and metabolic dysfunction.

bioRxiv · Nov 4, 2025 · PreprintPathology

GWAS defines pathogenic signaling pathways and prioritizes drug targets for IgA nephropathy

Krzysztof Kiryluk, Elena Sánchez, Shu‐Feng Zhou, Francesca Zanoni, Lili Liu, Nikol Mladkova, Atlas Khan, Maddalena Marasà, Jun Y. Zhang, Olivia Balderes, Simone Sanna‐Cherchi, Andrew S. Bomback, Pietro A. Canetta, Gerald B. Appel, Jai Radhakrishnan, , Claudia Izzi

This study identifies 30 genome-wide significant risk loci for IgA nephropathy, links them to inflammatory pathways, and prioritizes drug targets.

medRxiv · Nov 19, 2021 · PreprintGenetic & Genomic Medicine