Author

Douglas E. Wright

University of Kansas Medical CenterORCID 0000-0002-3748-7874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4

Frequent Co-Authors

Janelle M. Ryals· 2 shared Jarrid L. Jack· 2 shared Jonathan David EndersiD· 2 shared Julie A. ChristiansoniD· 2 shared Paige A. Lynch· 2 shared Patrycja PuchalskaiD· 2 shared Peter A. CrawfordiD· 2 shared Sarah K. ThomasiD· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Janelle M. Ryals

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ATP-Gated Potassium Channels Contribute to Ketogenic Diet-Mediated Analgesia in Mice.

Jonathan David Enders, Sarah K. Thomas, Paige A. Lynch, Jarrid L. Jack, Janelle M. Ryals, Patrycja Puchalska, Peter A. Crawford, Douglas E. Wright

This study shows that a ketogenic diet reduces pain in mice through ketone oxidation and activation of ATP-gated potassium channels.

Neurobiology of Pain · Jul 3, 2023Peer-reviewedNeuroscience

Ketolysis is Required for the Proper Development and Function of the Somatosensory Nervous System.

Jonathan David Enders, Jarrid L. Jack, Sarah K. Thomas, Paige A. Lynch, Sarah Lasnier, Xin Cao, M. Taylor Swanson, Janelle M. Ryals, John P. Thyfault, Patrycja Puchalska, Peter A. Crawford, Douglas E. Wright

This study shows that ketone metabolism is essential for the development and function of the somatosensory nervous system, with loss of ketolysis causing myelination deficits and proprioceptive impairments.

Experimental Neurology · Apr 24, 2023Peer-reviewedNeuroscience

Voluntary wheel running improves outcomes in an early life stress-induced model of urologic chronic pelvic pain syndrome in male mice

Isabella M. Fuentes, Brittni M. Jones, Aaron Daniel Brake, Angela N. Pierce, Olivia C. Eller, Rachel M. Supple, Douglas E. Wright, Julie A. Christianson

This study shows that voluntary wheel running reduces UCPPS symptoms in male mice with early life stress, improving mechanical sensitivity, bladder output, and mast cell degranulation.

Pain · Dec 29, 2020Peer-reviewedNeuroscience

Foot shock stress generates persistent widespread hypersensitivity and anhedonic behavior in an anxiety-prone strain of mice

Pau Yen Wu, Xiaofang Yang, Douglas E. Wright, Julie A. Christianson

This study shows that foot shock stress in anxiety-prone mice leads to persistent pain hypersensitivity and anhedonia, suggesting a model for understanding chronic pain and mood disorders in UCPPS patients.

Pain · Sep 21, 2019Peer-reviewedNeuroscience