Author

Fatima Mechta‐Grigoriou

InsermORCID 0000-0002-3751-6989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Yann KiefferiD· 2 shared Antonio CappuccioiD· 1 shared Catherine BrenneriD· 1 shared Christine PéchouxiD· 1 shared Clara NahmiasiD· 1 shared Coline Trichot· 1 shared Cynthia Seiler· 1 shared Damarys LoewiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Yann KiefferORCID

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2 papers

Recent·Most cited

Connecting mitochondrial metabolism and mitotic fidelity to control vulnerability of high grade serous ovarian cancer patients to taxane-based chemotherapy

Hadia Moindjie, Morgane Morin, Evanthia Pangou, Diego Chianese, Cynthia Seiler, Sylvie Rodrigues-Ferreira, Maria M. Haykal, Christine Péchoux, Florent Dingli, Damarys Loew, Yann Kieffer, Géraldine Gentric, Patricia Pautier, Philippe Dessen, Rafael José Argüello, , Clara Nahmias

This paper identifies syntabulin as a determinant of chemosensitivity in high-grade serous ovarian cancer by linking mitochondrial metabolism and mitotic fidelity.

bioRxiv · Jan 8, 2026 · PreprintCancer Biology

ICELLNET: a transcriptome-based framework to dissect intercellular communication

Floriane Noël, Lucile Massenet-Regad, Irit Carmi-Levy, Antonio Cappuccio, Maximilien Grandclaudon, Coline Trichot, Yann Kieffer, Fatima Mechta‐Grigoriou, Vassili Soumelis

ICELLNET integrates ligand-receptor interactions and communication scores to analyze cell-to-cell communication in transcriptomic data, revealing novel interactions in breast cancer and dendritic cells.

Nature Communications · Feb 17, 2021Peer-reviewedSystems Biology