Connecting mitochondrial metabolism and mitotic fidelity to control vulnerability of high grade serous ovarian cancer patients to taxane-based chemotherapy
Hadia Moindjie, Morgane Morin, Evanthia Pangou, Diego Chianese, Cynthia Seiler, Sylvie Rodrigues-Ferreira, Maria M. Haykal, Christine Péchoux, Florent Dingli, Damarys Loew, Yann Kieffer, Géraldine Gentric, Patricia Pautier, Philippe Dessen, Rafael José Argüello, , Clara Nahmias
This paper identifies syntabulin as a determinant of chemosensitivity in high-grade serous ovarian cancer by linking mitochondrial metabolism and mitotic fidelity.
bioRxiv · Jan 8, 2026 · PreprintCancer Biology