Author

Takemasa Sakaguchi

Hiroshima UniversityORCID 0000-0002-3754-1252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Airi Odawara· 1 shared Akima YamamotoiD· 1 shared Ayako Yamamoto· 1 shared Chika Arai· 1 shared DE Shankhajit· 1 shared Grace Naswa MakokhaiD· 1 shared Hideki ShibaiD· 1 shared Hidemasa U. BonoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMicrobiology

Airi Odawara

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapeutic Potential of the Novel Monoclonal Antibody 7-4G against HBsAg in a Mouse Model of Chronic Hepatitis B Virus Infection

Maidina Abuduwaili, Grace Naswa Makokha, Malihe Naderi, Hiroyuki Sakai, Akima Yamamoto, Takemasa Sakaguchi, Takehisa Matsumoto, Mikako Shirouzu, Seishi Kyoizumi, Ayako Yamamoto, Yoshiko Kubo, Miyuki Matsushita, Yoko Inoue, DE Shankhajit, Makoto Hijikata, Kazuaki Chayama

This study evaluates the antiviral activity of the monoclonal antibody 7-4G against HBsAg in a mouse model of chronic HBV infection, showing significant reduction in viral markers.

bioRxiv · Jul 26, 2026 · PreprintImmunology

Spontaneous mutations in braRS and braAB and the IS1181-related deletion of vraDE genes increase the susceptibility of Staphylococcus aureus clinical isolates to epidermin

Y Suzuki, Airi Odawara, Miki Kawada‐Matsuo, Junzo Hisatsune, Chika Arai, Saki Nishihama, Hideki Shiba, Motoyuki Sugai, Souichi Yanamoto, Takemasa Sakaguchi, Hitoshi Komatsuzawa

bioRxiv · Sep 27, 2025 · PreprintMicrobiology

Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal

Keiji Tanimoto, Kiichi Hirota, Takahiro Fukazawa, Yoshiyuki Matsuo, Toshihito Nomura, Tanuza Nazmul, Nobuyuki Hirohashi, Hidemasa U. Bono, Takemasa Sakaguchi

This study shows that AHR agonists like CSE, FICZ, and OMP reduce ACE2 expression, inhibiting SARS-CoV-2 infection in mammalian cells.

Scientific Reports · Aug 17, 2021Peer-reviewedMolecular Biology